Bronchial Tubes Structure, Functions, & Location | Bronchus Anatomy
Thin Filaments in Skeletal Muscle Fibers • Definition & Function
From the Z discs, the thin filaments extend inward toward the center of a sarcomere, where they partially overlap with the thick filaments.
Approximately 300-400 G actin (= globular actin) proteins make up most of a thin filament. The G actins attach end to end (= polymerize) to form two twisted strands. Together, the two strands are referred to as F actin (= fibrous actin).
Large nebulin proteins span the length of the F actins and help direct their assembly. The nebulins seem to function as “measuring sticks” that make sure the F-actins extend to the proper length.
After the F actins are constructed, capping proteins prevent them from depolymerizing or unraveling. The medial end of an F actin is presumably capped by tropomodulin and the lateral end by Cap Z. The Cap Z proteins are attached to the Z disc by actinin proteins.
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A troponin molecule is associated with each tropomyosin. When bound to calcium, the troponins move the tropomyosins so contraction can take place.